ACLY-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR37
Cell Type: CD8 T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: SIRT1
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a ACLY-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-SIRT1-phos) modification and TCA cycle-mediated (NUDT21-Acetyl-CoA-ATP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
SIRT1
RNA types
mRNAs
Modification
ac4C
Label
phos
RNA editing
A to I
Cell Type
CD8 T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-ac4C-METTL14-YTHDF2-ALKBH5-SIRT1-phos
Substrates
Acetyl-CoA
Cofactors
ATP
Pathway
TCA cycle
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Ovarian Cancers
RNA-binding proteins
NUDT21
Metabolic Reprogramming
TCA cycle-NUDT21-Acetyl-CoA-ATP
Target
ACLY
Alternative Names
ATP citrate lyase (ACLY
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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