AcsE-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR250
Cell Type: M2 macrophages
RNA writers: METTL16
RNA readers: YTHDF3
RNA erasers: FTO
Enzymes: PDH
RNA types: mRNAs
Modification: m5C
RNA editing: A to I
Short Description
This product is a acsE-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL16-YTHDF3-FTO-PDH-TET) modification and Gluconeogenesis-mediated (α-synuclein-SAM-ATP) metabolic analysis system.
RNA writers
METTL16
RNA readers
YTHDF3
RNA erasers
FTO
Enzymes
PDH
RNA types
mRNAs
Modification
m5C
Label
TET
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
mRNAs-m5C-METTL16-YTHDF3-FTO-PDH-TET
Substrates
SAM
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
NSD2 overexpression
Metabolic alteration
Upregulating pentose phosphate pathway
Targeting diseases
Glioma
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Gluconeogenesis-α-synuclein-SAM-ATP
Target
acsE
Alternative Names
acsE; 5-Methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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