Creative Biolabs-Immuno-oncology

ALT-targeted RNA Modification and Metabolomics Analysis Tool (CAT#: ITS-0524-CR226)

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Short Description
This product is a ALT-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL3-YTHDF1-FTO-MAT2A-spacer C9) modification and Glycolysis-mediated (CPEB4-SAM-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
MAT2A
RNA types
mRNAs
Modification
m1A
Label
spacer C9
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
cET, 2'-MOE
RNA Construction
mRNAs-m1A-METTL3-YTHDF1-FTO-MAT2A-spacer C9
Substrates
SAM
Cofactors
ADP
Pathway
Glycolysis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Esophageal Cancers
RNA-binding proteins
CPEB4
Metabolic Reprogramming
Glycolysis-CPEB4-SAM-ADP
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For Research Use Only | Not For Clinical Use

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