Creative Biolabs-Immuno-oncology

Anti-AFP (clone 5LF1G1G) SynExpress E1-mCh-I17-B Synthetic CD4+ T cells (CAT#: ITS-1224-CR964)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target AFP (clone 5LF1G1G). We employs the AAV (EF1α-mCherry-IL-17-BamHI) vector components and the SynExpress system of the Multiple base pair Insertion/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
AFP
Clone
5LF1G1G
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
IL-17
Insertion Sites
BamHI
Gene Modification
Insertion
Modification Domain
Multiple base pair
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
Microcarrier Culture
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For Research Use Only | Not For Clinical Use

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