Anti-ALK (clone ALK5L8P) SynExpress T7-mCh-cF-X Regulatory B cells

CAT#: ITS-1224-CR971
Clone: ALK5L8P
Host: Mouse
Cell Source: Regulatory B cells
Species Reactivity: Human
Connector Fragments: T7-mCherry-c-Fos-XbaI
Carrier Type: AAV
Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target ALK (clone ALK5L8P). We employs the AAV (T7-mCherry-c-Fos-XbaI) vector components and the SynExpress system of the Single base pair Knockout/Balancing feedback for a robust and sustained response against cancers.
Host
Mouse
Target
ALK
Clone
ALK5L8P
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
mCherry
Promoter
T7
Effector Gene
c-Fos
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.86
Cell Culture
Suspension Culture
Target
ALK
Alternative Names
ALK; CD246; NBLST3; anaplastic lymphoma receptor tyrosine kinase; ALK receptor tyrosine kinase; ALK (gene); ALK1
Gene ID
Q9UM73(Human); P97793(Mouse)
UniProt ID
238(Human); 11682(Mouse); 266802(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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