Anti-ANO1 (clone 5LE2ED1G) SynExpress E1-Cy5-I10-B Regulatory B cells

CAT#: ITS-1224-CR71
Clone: 5LE2ED1G
Host: Humanized
Cell Source: Regulatory B cells
Species Reactivity: Human
Connector Fragments: EF1α-Cy5-IL-10-BamHI
Carrier Type: AAV
Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target ANO1 (clone 5LE2ED1G). We employs the AAV (EF1α-Cy5-IL-10-BamHI) vector components and the SynExpress system of the Coding regions Deletion/Balancing feedback for a robust and sustained response against cancers.
Host
Humanized
Target
ANO1
Clone
5LE2ED1G
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
Cy5
Promoter
EF1α
Effector Gene
IL-10
Insertion Sites
BamHI
Gene Modification
Deletion
Modification Domain
Coding regions
Carrier Type
AAV
Transformation Accuracy
0.92
Cell Culture
Suspension Culture
Target
ANO1
Alternative Names
ANO1; DOG1; ORAOV2; TAOS2; TMEM16A; anoctamin 1
Gene ID
Q5XXA6(Human)
UniProt ID
55107(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
Online Inquiry