Creative Biolabs-Immuno-oncology

Anti-CD19 (clone 13677L) SynExpress C-mNe-I4-K Modified CD8+ T cells (CAT#: ITS-1224-CR932)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD19 (clone 13677L). We employs the pAS (CMV-mNeonGreen-IL-4-KpnI) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
CD19
Clone
13677L
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mNeonGreen
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
pAS
Transformation Accuracy
0.97
Cell Culture
3D Culture
Case Studies
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