Creative Biolabs-Immuno-oncology

Anti-CD2 (clone B3TI-422D2) SynExpress E1-mCh-I10-H Dendritic Cells (CAT#: ITS-1124-CR472)

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Description
This product utilizes dendritic cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD2 ( clone B3TI-422D2). We employs the pAS (EF1α-mCherry-IL-10-HindIII) vector components and the SynExpress system of the single base pair Deletion/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CD2
Clone
B3TI-422D2
Species Reactivity
Human
Cell Source
Dendritic cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
IL-10
Insertion Sites
HindIII
Gene Modification
Deletion
Modification Domain
Single base pair
Carrier Type
pAS
Transformation Accuracy
0.99
Cell Culture
3D Culture
Case Studies
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