Anti-CD22 (clone I1C1R122-2) SynExpress E1-mCh-NF-E CD8+ T Cells

CAT#: ITS-1124-CR28
Clone: I1C1R122-2
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: EF1α-mCherry-NF-κB-EcoRI
Carrier Type: AAV
Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD22 ( clone I1C1R122-2). We employs the AAV (EF1α-mCherry-NF-κB-EcoRI) vector components and the SynExpress system of the single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CD22
Clone
I1C1R122-2
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
NF-κB
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.91
Cell Culture
3D Culture
Target
CD22
Alternative Names
CD22; SIGLEC-2; SIGLEC2; CD22 molecule
Gene ID
P16871(Human)
UniProt ID
933(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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