Creative Biolabs-Immuno-oncology

Anti-CD22 (clone IOCR28) SynExpress C-mCh-I10-Sa CD4+ T Cells (CAT#: ITS-1124-CR496)

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Description
This product utilizes CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD22 ( clone IOCR28). We employs the AAV (CMV-mCherry-IL-10-SaII) vector components and the SynExpress system of the single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Humanized
Target
CD22
Clone
IOCR28
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
SaII
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.93
Cell Culture
3D Culture
Case Studies
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