Creative Biolabs-Immuno-oncology

Anti-CD47 (clone 0Z37J-Z1G) SynExpress E1-mCh-I10-H Modified CD8+ T cells (CAT#: ITS-1224-CR1628)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD47 (clone 0Z37J-Z1G). We employs the Adenovirus (EF1α-mCherry-IL-10-HindIII) vector components and the SynExpress system of the Single base pair Deletion/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
CD47
Clone
0Z37J-Z1G
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
IL-10
Insertion Sites
HindIII
Gene Modification
Deletion
Modification Domain
Single base pair
Carrier Type
Adenovirus
Transformation Accuracy
0.98
Cell Culture
3D Culture
Case Studies
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