Anti-CD70 (clone CLB-2EF2E) SynExpress C-mNe-I4-K Modified CD8+ T cells

CAT#: ITS-1224-CR1802
Clone: CLB-2EF2E
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-mNeonGreen-IL-4-KpnI
Carrier Type: pCDNA
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD70 (clone CLB-2EF2E). We employs the pCDNA (CMV-mNeonGreen-IL-4-KpnI) vector components and the SynExpress system of the Exons Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CD70
Clone
CLB-2EF2E
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mNeonGreen
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Base Editing
Modification Domain
Exons
Carrier Type
pCDNA
Transformation Accuracy
0.94
Cell Culture
3D Culture
Target
CD70
Alternative Names
CD70; Cluster of Differentiation 70
Gene ID
P32970(Human)
UniProt ID
970(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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