Creative Biolabs-Immuno-oncology

Anti-CD70 (clone HJLA) SynExpress C-mCh-I4-E Modified CD8+ T cells (CAT#: ITS-1224-CR1766)

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Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD70 (clone HJLA). We employs the pCDNA (CMV-mCherry-IL-4-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
CD70
Clone
HJLA
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
pCDNA
Transformation Accuracy
0.94
Cell Culture
3D Culture
Case Studies
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