Creative Biolabs-Immuno-oncology

Anti-CD70 (clone VH-8P-VL) SynExpress SV-R-I17-E Regulatory B cells (CAT#: ITS-1224-CR1805)

DatasheetDatasheet
Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD70 (clone VH-8P-VL). We employs the AAV (SV40-RFP-IL-17-EcoRI) vector components and the SynExpress system of the Single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
humanized
Target
CD70
Clone
VH-8P-VL
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
RFP
Promoter
SV40
Effector Gene
IL-17
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.95
Cell Culture
Suspension Culture
Case Studies
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