Creative Biolabs-Immuno-oncology

Anti-CDH17 (clone xp2E3) SynExpress T7-mCh-I10-Sa Synthetic CD4+ T cells (CAT#: ITS-1224-CR743)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CDH17 (clone xp2E3). We employs the AAV (T7-mCherry-IL-10-SaII) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CDH17
Clone
xp2E3
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
T7
Effector Gene
IL-10
Insertion Sites
SaII
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.87
Cell Culture
Suspension Culture
Case Studies
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