Creative Biolabs-Immuno-oncology

Anti-CDH3 (clone xp2E4I) SynExpress T7-mCh-cJ-K Modified CD8+ T cells (CAT#: ITS-1224-CR754)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CDH3 (clone xp2E4I). We employs the Lentivirus (T7-mCherry-c-Jun-KpnI) vector components and the SynExpress system of the Single base pair RNA Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
CDH3
Clone
xp2E4I
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
T7
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
RNA Editing
Modification Domain
Single base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.92
Cell Culture
Microcarrier Culture
Case Studies
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