Creative Biolabs-Immuno-oncology

Anti-CEACAM5 (clone hMN1G5L) SynExpress pL-G-NF-B Synthetic CD4+ T cells (CAT#: ITS-1224-CR800)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CEACAM5 (clone hMN1G5L). We employs the AAV (pL-GFP-NF-κB-BamHI) vector components and the SynExpress system of the Single base pair Knockout/Delayed feedback for a robust and sustained response against cancers.
Host
Humanized
Target
CEACAM5
Clone
hMN1G5L
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
GFP
Promoter
pL
Effector Gene
NF-κB
Insertion Sites
BamHI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
3D Culture
Case Studies
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