Creative Biolabs-Immuno-oncology

Anti-Claudin18.2 (clone 1G7J5LD1G0Z) SynExpress T7-mCh-I4-K Modified CD8+ T cells (CAT#: ITS-1224-CR842)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target Claudin18.2 (clone 1G7J5LD1G0Z). We employs the pCDNA (T7-mCherry-IL-4-KpnI) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
Claudin18.2
Clone
1G7J5LD1G0Z
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
T7
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
pCDNA
Transformation Accuracy
0.94
Cell Culture
3D Culture
Case Studies
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