Creative Biolabs-Immuno-oncology

Anti-CLDN18.2 (clone DF4589I) SynExpress T7-YF-I17-Sm γδ T cells (CAT#: ITS-1224-CR1914)

DatasheetDatasheet
Description
This product utilizes γδ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CLDN18.2 (clone DF4589I). We employs the AAV (T7-YFP-IL-17-SmaI) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CLDN18.2
Clone
DF4589I
Species Reactivity
Human
Cell Source
γδ T cells
Sensor Gene
YFP
Promoter
T7
Effector Gene
IL-17
Insertion Sites
SmaI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
Suspension Culture
Case Studies
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