This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target CLEC12A (clone M2E6Z). We employs the pCDNA (pL-Cy2-IL-17-BamHI) vector components and the SynExpress system of the Coding regions Deletion/Delayed feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CLEC12A
Clone
M2E6Z
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
Cy2
Promoter
pL
Effector Gene
IL-17
Insertion Sites
BamHI
Gene Modification
Deletion
Modification Domain
Coding regions
Carrier Type
pCDNA
Transformation Accuracy
0.97
Cell Culture
3D Culture
Target
CLEC12A
Alternative Names
CLEC12A; CLL-1; CLL1; DCAL-2; MICL; CD371; C-type lectin domain family 12 member A
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.