Anti-CSPG4 (clone D2EA-1GH1G2E) SynExpress C-mNe-β-Sm γδ T cells

CAT#: ITS-1224-CR884
Clone: D2EA-1GH1G2E
Host: Human
Cell Source: γδ T cells
Species Reactivity: Human
Connector Fragments: CMV-mNeonGreen-β-catenin-SmaI
Carrier Type: AAV
Description
This product utilizes γδ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CSPG4 (clone D2EA-1GH1G2E). We employs the AAV (CMV-mNeonGreen-β-catenin-SmaI) vector components and the SynExpress system of the Exons Deletion/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
CSPG4
Clone
D2EA-1GH1G2E
Species Reactivity
Human
Cell Source
γδ T cells
Sensor Gene
mNeonGreen
Promoter
CMV
Effector Gene
β-catenin
Insertion Sites
SmaI
Gene Modification
Deletion
Modification Domain
Exons
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
3D Culture
Target
CSPG4
Alternative Names
CSPG4; HMW-MAA; MCSP; MCSPG; MEL-CSPG; MSK16; NG2; chondroitin sulfate proteoglycan 4; CSPG4A
Gene ID
Q6UVK1(Human); Q8VHY0(Mouse); Q00657(Rat)
UniProt ID
1464(Human); 121021(Mouse); 81651(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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