Creative Biolabs-Immuno-oncology

Anti-DNM2 (clone 1G0ZC2E3) SynExpress pB-mCh-cF-Sp Regulatory B cells (CAT#: ITS-1224-CR2201)

DatasheetDatasheet
Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target DNM2 (clone 1G0ZC2E3). We employs the Retrovirus (pBAD-mCherry-c-Fos-SpeI) vector components and the SynExpress system of the Single base pair Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DNM2
Clone
1G0ZC2E3
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
mCherry
Promoter
pBAD
Effector Gene
c-Fos
Insertion Sites
SpeI
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
Retrovirus
Transformation Accuracy
0.98
Cell Culture
3D Culture
Case Studies
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