Anti-DR5 (clone 2EF9Q) SynExpress C-mSc-GR-X Synthetic CD4+ T cells

CAT#: ITS-1224-CR2287
Clone: 2EF9Q
Host: Mouse
Cell Source: Synthetic CD4+ T cells
Species Reactivity: Human
Connector Fragments: CMV-mScarlet-GR-XbaI
Carrier Type: pCDNA
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone 2EF9Q). We employs the pCDNA (CMV-mScarlet-GR-XbaI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DR5
Clone
2EF9Q
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mScarlet
Promoter
CMV
Effector Gene
GR
Insertion Sites
XbaI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
pCDNA
Transformation Accuracy
0.89
Cell Culture
3D Culture
Target
DR5
Alternative Names
TNFRSF10B; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; tumor necrosis factor receptor superfamily member 10b; TNF receptor superfamily member 10b
Gene ID
O14763(Human)
UniProt ID
8795(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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