Anti-DR5 (clone AU1G1G) SynExpress pL-mSc-cJ-H Modified CD8+ T cells

CAT#: ITS-1224-CR2278
Clone: AU1G1G
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: pL-mScarlet-c-Jun-HindIII
Carrier Type: AAV
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone AU1G1G). We employs the AAV (pL-mScarlet-c-Jun-HindIII) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
DR5
Clone
AU1G1G
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mScarlet
Promoter
pL
Effector Gene
c-Jun
Insertion Sites
HindIII
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.87
Cell Culture
Suspension Culture
Target
DR5
Alternative Names
TNFRSF10B; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; tumor necrosis factor receptor superfamily member 10b; TNF receptor superfamily member 10b
Gene ID
O14763(Human)
UniProt ID
8795(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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