Creative Biolabs-Immuno-oncology

Anti-DR5 (clone AU1G1G) SynExpress pL-mSc-cJ-H Modified CD8+ T cells (CAT#: ITS-1224-CR2278)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone AU1G1G). We employs the AAV (pL-mScarlet-c-Jun-HindIII) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
DR5
Clone
AU1G1G
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mScarlet
Promoter
pL
Effector Gene
c-Jun
Insertion Sites
HindIII
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.87
Cell Culture
Suspension Culture
Case Studies
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