Creative Biolabs-Immuno-oncology

Anti-DR5 (clone DR5L-0Z1G-1G) SynExpress p15-mCh-I10-Sa Modified CD8+ T cells (CAT#: ITS-1224-CR2282)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone DR5L-0Z1G-1G). We employs the HBV (p15A-mCherry-IL-10-SaII) vector components and the SynExpress system of the DNA methylation sites Knock-in/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DR5
Clone
DR5L-0Z1G-1G
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
p15A
Effector Gene
IL-10
Insertion Sites
SaII
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
HBV
Transformation Accuracy
0.87
Cell Culture
Adherent Culture
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For Research Use Only | Not For Clinical Use

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