Anti-DR5 (clone HTRA-8P) SynExpress E1-G-cF-X Modified CD8+ T cells

CAT#: ITS-1224-CR2276
Clone: HTRA-8P
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: EF1α-GFP-c-Fos-XbaI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone HTRA-8P). We employs the Lentivirus (EF1α-GFP-c-Fos-XbaI) vector components and the SynExpress system of the Introns Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
DR5
Clone
HTRA-8P
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
EF1α
Effector Gene
c-Fos
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Introns
Carrier Type
Lentivirus
Transformation Accuracy
0.86
Cell Culture
Suspension Culture
Target
DR5
Alternative Names
TNFRSF10B; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; tumor necrosis factor receptor superfamily member 10b; TNF receptor superfamily member 10b
Gene ID
O14763(Human)
UniProt ID
8795(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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