Anti-DR5 (clone MD5L-1G) SynExpress E1-TG-AR-H Dendritic cells

CAT#: ITS-1224-CR2273
Clone: MD5L-1G
Host: Mouse
Cell Source: Dendritic cells
Species Reactivity: Human
Connector Fragments: EF1α-TurboGFP-AR-HindIII
Carrier Type: Adenovirus
Description
This product utilizes Dendritic cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone MD5L-1G). We employs the Adenovirus (EF1α-TurboGFP-AR-HindIII) vector components and the SynExpress system of the DNA methylation sites Knock-in/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DR5
Clone
MD5L-1G
Species Reactivity
Human
Cell Source
Dendritic cells
Sensor Gene
TurboGFP
Promoter
EF1α
Effector Gene
AR
Insertion Sites
HindIII
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
Adenovirus
Transformation Accuracy
0.86
Cell Culture
Adherent Culture
Target
DR5
Alternative Names
TNFRSF10B; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; tumor necrosis factor receptor superfamily member 10b; TNF receptor superfamily member 10b
Gene ID
O14763(Human)
UniProt ID
8795(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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