Anti-DR5 (clone ZP1G2E2E6Z) SynExpress trc-Cy2-I17-E Engineered Tregs

CAT#: ITS-1224-CR2269
Clone: ZP1G2E2E6Z
Host: Human
Cell Source: Engineered Tregs
Species Reactivity: Human
Connector Fragments: trc-Cy2-IL-17-EcoRI
Carrier Type: Lentivirus
Description
This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone ZP1G2E2E6Z). We employs the Lentivirus (trc-Cy2-IL-17-EcoRI) vector components and the SynExpress system of the Exons Base Editing/Delayed feedback for a robust and sustained response against cancers.
Host
Human
Target
DR5
Clone
ZP1G2E2E6Z
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
Cy2
Promoter
trc
Effector Gene
IL-17
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
Exons
Carrier Type
Lentivirus
Transformation Accuracy
0.86
Cell Culture
3D Culture
Target
DR5
Alternative Names
TNFRSF10B; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; tumor necrosis factor receptor superfamily member 10b; TNF receptor superfamily member 10b
Gene ID
O14763(Human)
UniProt ID
8795(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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