This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target DR6 (clone 2EC1G1G). We employs the Adenovirus (T7-GFP-NF-κB-XbaI) vector components and the SynExpress system of the DNA methylation sites Knock-in/Delayed feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DR6
Clone
2EC1G1G
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
GFP
Promoter
T7
Effector Gene
NF-κB
Insertion Sites
XbaI
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
Adenovirus
Transformation Accuracy
0.98
Cell Culture
Plate Culture
Target
DR6
Alternative Names
TNFRSF21; BM-018; CD358; DR6; tumor necrosis factor receptor superfamily member 21; TNF receptor superfamily member 21
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.