Anti-DSC3 (clone 5L5L3) SynExpress E1-mCh-I4-X Modified CD8+ T cells

CAT#: ITS-1224-CR2328
Clone: 5L5L3
Host: Rat
Cell Source: Modified CD8+ T cells
Species Reactivity: Mouse
Connector Fragments: EF1α-mCherry-IL-4-XbaI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DSC3 (clone 5L5L3). We employs the Lentivirus (EF1α-mCherry-IL-4-XbaI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Rat
Target
DSC3
Clone
5L5L3
Species Reactivity
Mouse
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
IL-4
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.91
Cell Culture
Adherent Culture
Target
DSC3
Alternative Names
DSC3; CDHF3; DSC; DSC1; DSC2; DSC4; HT-CP; desmocollin 3
Gene ID
Q14574(Human); P55850(Mouse)
UniProt ID
1825(Human); 13507(Mouse); 307563(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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