Creative Biolabs-Immuno-oncology

Anti-DSG1 (clone M5L9Q3) SynExpress pU-mCh-cF-Sp Regulatory B cells (CAT#: ITS-1224-CR2351)

DatasheetDatasheet
Description
This product utilizes Regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target DSG1 (clone M5L9Q3). We employs the AAV (pUC-mCherry-c-Fos-SpeI) vector components and the SynExpress system of the Exons Inversion/Balancing feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DSG1
Clone
M5L9Q3
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
mCherry
Promoter
pUC
Effector Gene
c-Fos
Insertion Sites
SpeI
Gene Modification
Inversion
Modification Domain
Exons
Carrier Type
AAV
Transformation Accuracy
0.93
Cell Culture
Suspension Culture
Case Studies
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