Creative Biolabs-Immuno-oncology

Anti-DSG2 (clone 4I2E0Z) SynExpress pB-Cy5-β-E NK cells (CAT#: ITS-1224-CR2355)

DatasheetDatasheet
Description
This product utilizes NK cells that have been engineered with our proprietary GeneCircuit technology to specifically target DSG2 (clone 4I2E0Z). We employs the AAV (pBAD-Cy5-β-catenin-EcoRI) vector components and the SynExpress system of the Single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DSG2
Clone
4I2E0Z
Species Reactivity
Human
Cell Source
NK cells
Sensor Gene
Cy5
Promoter
pBAD
Effector Gene
β-catenin
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.91
Cell Culture
3D Culture
Case Studies
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