Creative Biolabs-Immuno-oncology

Anti-DSG3 (clone 5LG1G1G) SynExpress C-Cy2-I17-E Engineered Tregs (CAT#: ITS-1224-CR2370)

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Description
This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target DSG3 (clone 5LG1G1G). We employs the AAV (CMV-Cy2-IL-17-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DSG3
Clone
5LG1G1G
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
Cy2
Promoter
CMV
Effector Gene
IL-17
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.88
Cell Culture
Suspension Culture
Case Studies
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