Anti-DSG3 (clone 5LG1G1G) SynExpress C-Cy2-I17-E Engineered Tregs

CAT#: ITS-1224-CR2370
Clone: 5LG1G1G
Host: Mouse
Cell Source: Engineered Tregs
Species Reactivity: Human
Connector Fragments: CMV-Cy2-IL-17-EcoRI
Carrier Type: AAV
Description
This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target DSG3 (clone 5LG1G1G). We employs the AAV (CMV-Cy2-IL-17-EcoRI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DSG3
Clone
5LG1G1G
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
Cy2
Promoter
CMV
Effector Gene
IL-17
Insertion Sites
EcoRI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.88
Cell Culture
Suspension Culture
Target
DSG3
Alternative Names
DSG3; CDHF6; PVA; desmoglein 3; ABOLM
Gene ID
P32926(Human)
UniProt ID
1830(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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