Creative Biolabs-Immuno-oncology

Anti-DSG3 (clone 7JB9Q) SynExpress C-mKa-cJ-K Modified CD8+ T cells (CAT#: ITS-1224-CR2379)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DSG3 (clone 7JB9Q). We employs the pAS (CMV-mKate-c-Jun-KpnI) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DSG3
Clone
7JB9Q
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
CMV
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
pAS
Transformation Accuracy
0.95
Cell Culture
3D Culture
Case Studies
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