Anti-E2F1 (clone L0Z35L6Z) SynExpress SV-G-I10-K Modified CD8+ T cells

CAT#: ITS-1224-CR2451
Clone: L0Z35L6Z
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human; Rat
Connector Fragments: SV40-GFP-IL-10-KpnI
Carrier Type: pAS
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target E2F1 (clone L0Z35L6Z). We employs the pAS (SV40-GFP-IL-10-KpnI) vector components and the SynExpress system of the Single base pair Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
E2F1
Clone
L0Z35L6Z
Species Reactivity
Human; Rat
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
SV40
Effector Gene
IL-10
Insertion Sites
KpnI
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
pAS
Transformation Accuracy
0.95
Cell Culture
3D Culture
Target
E2F1
Alternative Names
E2F1; E2F-1; RBAP1; RBBP3; RBP3; E2F transcription factor 1
Gene ID
Q01094(Human); O09139(Rat)
UniProt ID
1869(Human); 399489(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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