Creative Biolabs-Immuno-oncology

Anti-E2F1 (clone L0Z35L6Z) SynExpress SV-G-I10-K Modified CD8+ T cells (CAT#: ITS-1224-CR2451)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target E2F1 (clone L0Z35L6Z). We employs the pAS (SV40-GFP-IL-10-KpnI) vector components and the SynExpress system of the Single base pair Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
E2F1
Clone
L0Z35L6Z
Species Reactivity
Human; Rat
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
SV40
Effector Gene
IL-10
Insertion Sites
KpnI
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
pAS
Transformation Accuracy
0.95
Cell Culture
3D Culture
Case Studies
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