Creative Biolabs-Immuno-oncology

Anti-Env (clone PGT1G4I3) SynExpress pB-mCh-I10-B Synthetic CD4+ T cells (CAT#: ITS-1224-CR623)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target Env (clone PGT1G4I3). We employs the Lentivirus (pBAD-mCherry-IL-10-BamHI) vector components and the SynExpress system of the miRNA Prime Editing/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
Env
Clone
PGT1G4I3
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
pBAD
Effector Gene
IL-10
Insertion Sites
BamHI
Gene Modification
Prime Editing
Modification Domain
miRNA
Carrier Type
Lentivirus
Transformation Accuracy
0.98
Cell Culture
Suspension Culture
Case Studies
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