Anti-EphA2 (clone H-448-2-T2) SynExpress C-G-I10-X CD8+ T Cells

CAT#: ITS-1124-CR397
Clone: H-448-2-T2
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-GFP-IL-10-XbaI
Carrier Type: AAV
Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target EphA2 ( clone H-448-2-T2). We employs the AAV (CMV-GFP-IL-10-XbaI) vector components and the SynExpress system of the single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
EphA2
Clone
H-448-2-T2
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.89
Cell Culture
Suspension Culture
Target
EphA2
Alternative Names
EPHA2; Epha2; AW545284; Eck; Myk2; Sek-2; Sek2; ARCC2; CTPA; CTPP1; CTRCT6; EPH receptor A2; ECK
Gene ID
P02771(Human); P02772(Mouse); P02773(Rat)
UniProt ID
1969(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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