Creative Biolabs-Immuno-oncology

Anti-EphA5 (clone 1G1GC1G2E) SynExpress pU-Cy2-I17-B Synthetic CD4+ T cells (CAT#: ITS-1224-CR653)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target EphA5 (clone 1G1GC1G2E). We employs the Retrovirus (pUC-Cy2-IL-17-BamHI) vector components and the SynExpress system of the Single base pair Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
EphA5
Clone
1G1GC1G2E
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
Cy2
Promoter
pUC
Effector Gene
IL-17
Insertion Sites
BamHI
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
Retrovirus
Transformation Accuracy
0.91
Cell Culture
Suspension Culture
Case Studies
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