Creative Biolabs-Immuno-oncology

Anti-FAP (clone MFP6D) SynExpress SV-mCh-NF-X Engineered Tregs (CAT#: ITS-1124-CR448)

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Description
This product utilizes engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target FAP ( clone MFP6D). We employs the pAS (SV40-mCherry-NF-κB-XbaI) vector components and the SynExpress system of the single base pair Base Editing/Delayed feedback for a robust and sustained response against cancers.
Host
Human
Target
FAP
Clone
MFP6D
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
SV40
Effector Gene
NF-κB
Insertion Sites
XbaI
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
pAS
Transformation Accuracy
0.85
Cell Culture
3D Culture
Case Studies
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