Anti-FOLH1 (clone IO-453N2E) SynExpress pB-mCh-I10-B Modified CD8+ T cells

CAT#: ITS-1224-CR418
Clone: IO-453N2E
Host: Humanized
Cell Source: Modified CD8+ T cells
Species Reactivity: human
Connector Fragments: pBAD-mCherry-IL-10-BamHI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target FOLH1 (clone IO-453N2E). We employs the Lentivirus (pBAD-mCherry-IL-10-BamHI) vector components and the SynExpress system of the Exons RNA Editing/Positive feedback for a robust and sustained response against cancers.
Host
Humanized
Target
FOLH1
Clone
IO-453N2E
Species Reactivity
human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
pBAD
Effector Gene
IL-10
Insertion Sites
BamHI
Gene Modification
RNA Editing
Modification Domain
Exons
Carrier Type
Lentivirus
Transformation Accuracy
0.86
Cell Culture
Suspension Culture
Target
FOLH1
Alternative Names
FOLH1; FGCP; FOLH; GCP2; GCPII; NAALAD1; NAALAdase; PSM; PSMA; mGCP; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1
Gene ID
Q8TCG1(Human); Q8BWY9(Mouse)
UniProt ID
2346(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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