Anti-FOLR1 (clone ML-2D3) SynExpress E1-mCh-NF-P Engineered Tregs

CAT#: ITS-1124-CR208
Clone: ML-2D3
Host: human
Cell Source: Engineered Tregs
Species Reactivity: human
Connector Fragments: EF1α-mCherry-NF-κB-PstI
Carrier Type: AAV
Description
This product utilizes engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target FOLR1 ( clone ML-2D3). We employs the AAV (EF1α-mCherry-NF-κB-PstI) vector components and the SynExpress system of the single base pair Knockout/Delayed feedback for a robust and sustained response against cancers.
Host
human
Target
FOLR1
Clone
ML-2D3
Species Reactivity
human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
NF-κB
Insertion Sites
PstI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
3D Culture
Target
FOLR1
Alternative Names
FOLR1; FBP; FOLR; Folate receptor 1; folate receptor 1 (adult); folate receptor alpha; FRalpha; NCFTD
UniProt ID
2348(Human); 171049 Rat(Mouse)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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