Creative Biolabs-Immuno-oncology

Anti-FOLR1 (clone ML-2D3) SynExpress E1-mCh-NF-P Engineered Tregs (CAT#: ITS-1124-CR208)

DatasheetDatasheet
Description
This product utilizes engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target FOLR1 ( clone ML-2D3). We employs the AAV (EF1α-mCherry-NF-κB-PstI) vector components and the SynExpress system of the single base pair Knockout/Delayed feedback for a robust and sustained response against cancers.
Host
human
Target
FOLR1
Clone
ML-2D3
Species Reactivity
human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
NF-κB
Insertion Sites
PstI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
3D Culture
Case Studies
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