Creative Biolabs-Immuno-oncology

Anti-GD2 (clone OL6GF4) SynExpress SP-mCh-NF-P Engineered Tregs (CAT#: ITS-1224-CR1019)

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Description
This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target GD2 (clone OL6GF4). We employs the AAV (SP6-mCherry-NF-κB-PstI) vector components and the SynExpress system of the Single base pair Deletion/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
GD2
Clone
OL6GF4
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
SP6
Effector Gene
NF-κB
Insertion Sites
PstI
Gene Modification
Deletion
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.91
Cell Culture
Suspension Culture
Case Studies
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