Creative Biolabs-Immuno-oncology

Anti-GITR (clone 45A8P) SynExpress C-G-cF-X Synthetic CD4+ T cells (CAT#: ITS-1224-CR472)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone 45A8P). We employs the AAV (CMV-GFP-c-Fos-XbaI) vector components and the SynExpress system of the Coding regions Deletion/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
GITR
Clone
45A8P
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
GFP
Promoter
CMV
Effector Gene
c-Fos
Insertion Sites
XbaI
Gene Modification
Deletion
Modification Domain
Coding regions
Carrier Type
AAV
Transformation Accuracy
0.92
Cell Culture
Suspension Culture
Case Studies
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