Anti-GITR (clone pab1G9Q6Z7J) SynExpress pB-BF-I17-X Modified CD8+ T cells

CAT#: ITS-1224-CR484
Clone: pab1G9Q6Z7J
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: pBAD-BFP-IL-17-XbaI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone pab1G9Q6Z7J). We employs the Lentivirus (pBAD-BFP-IL-17-XbaI) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
GITR
Clone
pab1G9Q6Z7J
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
pBAD
Effector Gene
IL-17
Insertion Sites
XbaI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
Lentivirus
Transformation Accuracy
0.98
Cell Culture
Suspension Culture
Target
GITR
Alternative Names
TNFRSF18; AITR; CD357; GITR; GITR-D; tumor necrosis factor receptor superfamily member 18; TNF receptor superfamily member 18; ENERGEN
Gene ID
P02771(Human); P02772(Mouse); P02773(Rat)
UniProt ID
8784(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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