Creative Biolabs-Immuno-oncology

Anti-GPC1 (clone M2E4R8D) SynExpress pB-BF-I4-K CD8+ T Cells (CAT#: ITS-1124-CR257)

DatasheetDatasheet
Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPC1 ( clone M2E4R8D). We employs the HBV (pBAD-BFP-IL-4-KpnI) vector components and the SynExpress system of the introns Knockout/Negative feedback for a robust and sustained response against cancers.
Host
humanized
Target
GPC1
Clone
M2E4R8D
Species Reactivity
human
Cell Source
Modified CD8+ T cells
Sensor Gene
BFP
Promoter
pBAD
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Introns
Carrier Type
HBV
Transformation Accuracy
0.98
Cell Culture
Adherent Culture
Case Studies
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