Anti-GPC3 (clone M6B32D) SynExpress SV-mKa-I10-E CD8+ T Cells

CAT#: ITS-1124-CR261
Clone: M6B32D
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: SV40-mKate-IL-10-EcoRI
Carrier Type: Retrovirus
Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPC3 ( clone M6B32D). We employs the Retrovirus (SV40-mKate-IL-10-EcoRI) vector components and the SynExpress system of the single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
GPC3
Clone
M6B32D
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
SV40
Effector Gene
IL-10
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Retrovirus
Transformation Accuracy
0.85
Cell Culture
Adherent Culture
Target
GPC3
Alternative Names
GPC3; DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1; Glypican 3
Gene ID
P04083(Human); P10107(Mouse); P07153(Rat)
UniProt ID
2719(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
Online Inquiry