This product utilizes dendritic cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPRC5D ( clone GB3602DF). We employs the AAV (trc-mCherry-AR-HindIII) vector components and the SynExpress system of the exons Deletion/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
GPRC5D
Clone
GB3602DF
Species Reactivity
Human
Cell Source
Dendritic cells
Sensor Gene
mCherry
Promoter
trc
Effector Gene
AR
Insertion Sites
HindIII
Gene Modification
Deletion
Modification Domain
Exons
Carrier Type
AAV
Transformation Accuracy
0.94
Cell Culture
3D Culture
Target
GPRC5D
Alternative Names
GPRC5D; G protein-coupled receptor; class C; group 5; member D; G protein-coupled receptor class C group 5 member D
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.