Creative Biolabs-Immuno-oncology

Anti-GPRC5D (clone SP60) SynExpress E1-mKa-cJ-X CD8+ T Cells (CAT#: ITS-1124-CR297)

DatasheetDatasheet
Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPRC5D ( clone SP60). We employs the Retrovirus (EF1α-mKate-c-Jun-XbaI) vector components and the SynExpress system of the single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
GPRC5D
Clone
SP60
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
EF1α
Effector Gene
c-Jun
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Retrovirus
Transformation Accuracy
0.86
Cell Culture
Adherent Culture
Case Studies
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