Anti-GRP78 (clone D1GDW) SynExpress C-Cy5-I4-H Modified CD8+ T cells

CAT#: ITS-1224-CR434
Clone: D1GDW
Host: Humanized
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-Cy5-IL-4-HindIII
Carrier Type: pCDNA
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GRP78 (clone D1GDW). We employs the pCDNA (CMV-Cy5-IL-4-HindIII) vector components and the SynExpress system of the Single base pair Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Humanized
Target
GRP78
Clone
D1GDW
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
Cy5
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
HindIII
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
pCDNA
Transformation Accuracy
0.96
Cell Culture
3D Culture
Target
GRP78
Alternative Names
HSPA5; BIP; GRP78; HEL-S-89n; MIF2; Binding immunoglobulin protein; heat shock protein family A (Hsp70) member 5; GRP78/Bip
Gene ID
P02771(Human); P02772(Mouse); P02773(Rat)
UniProt ID
3309(Human); 14828(Mouse); 25617(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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