Anti-GRP78 (clone D345Y) SynExpress E1-G-I17-B Engineered Tregs

CAT#: ITS-1224-CR435
Clone: D345Y
Host: Humanized
Cell Source: Engineered Tregs
Species Reactivity: Human
Connector Fragments: EF1α-GFP-IL-17-BamHI
Carrier Type: Lentivirus
Description
This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target GRP78 (clone D345Y). We employs the Lentivirus (EF1α-GFP-IL-17-BamHI) vector components and the SynExpress system of the miRNA Knockout/Delayed feedback for a robust and sustained response against cancers.
Host
Humanized
Target
GRP78
Clone
D345Y
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
GFP
Promoter
EF1α
Effector Gene
IL-17
Insertion Sites
BamHI
Gene Modification
Knockout
Modification Domain
miRNA
Carrier Type
Lentivirus
Transformation Accuracy
0.98
Cell Culture
Aseptic Culture
Target
GRP78
Alternative Names
HSPA5; BIP; GRP78; HEL-S-89n; MIF2; Binding immunoglobulin protein; heat shock protein family A (Hsp70) member 5; GRP78/Bip
Gene ID
P02771(Human); P02772(Mouse); P02773(Rat)
UniProt ID
3309(Human); 14828(Mouse); 25617(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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